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Kigtropin 10iu Recombinant Human Growth Hormone for Injection NAME OF THE MEDICINAL PRODUCT Generic Name: Recombinant Human Growth HormoneTrade Name: KIGTROPIN INGREDIENTS Recombinant Human Growth Hormone and excipients.Molecular Formula: C990H1528N262O300S7 with 191 amino acids residues.Molecular Weight: 22125DOrigin of the Active Ingredient: KIGTROPIN is a RecombinantsHuman Growth Hormone. KIGTROPIN is produced by recombinant DNAtechnology in E.coli secretion expression system. KIGTROPIN has thesame amino acid sequence with 191 residues as the native human growthhormone produced in the human body.. CHARACTERS White Lyophilized powder. INDICATION Growth failure of children due to endogenous growth hormonedeficiency (GHD).In adults with growth hormone deficiency, KIGTROPIN reducesfat mass, increases muscle mass and improves energy, vitality andsubjective well-being. In patients suffering from severe burns, AIDSassociated muscle wasting, or undergoing major operations, KIGTROPINpromotes wound healing, attenuates the protein-catabolic response andimproves whole-body nitrogen condition after operation. SPECIFICATIONS 10IU/3.7mg/1.0ml/vial DOSAGE AND ADMINISTRATION Before administration, add 1ml of sterile water for injectionto the rhGH vial of Lyophilized powder along the wall slowly. Shake itgently to fully dissolve the powder to get clarified solution. DO NOTshake violently.For anti-aging, general health & healing, fat mobilization, adose of 2-3 IU's per day will be sufficient for the majority. A doseof 1.5 to 2.0 IU's is considered to be a full replacement dose forthose in their middle-age and beyond.For gaining lean muscle and substantially improving bodycomposition, a dose of 4-8 IUs per day will be necessary. Most peoplewill respond very well at a dose of 4-5 IU's per day. For maximumbenefit in this regard, the addition of Testosterone, Insulin, andlow-dose t3 would be something to seriously consider. More on this inour comparative cycle guide of HGH/Insulin/IGF.The recommended dosage for injection is 0.1-0.15IU/kg/day,inject before sleeping daily at the same time and the injection siteshould be changes frequently to prevent lipoatrophy at the site, orfollow the physician's advice. ADVERSE REACTIONS Growth hormone may induce transient hyperglycosemia, whichusually recover to normal level over time or after drugdiscontinuation.About 1% children with microsomia in the clinical trialpresented side effects, which usually presented transient reactions atthe injection site (pain, tingling numbness, red swelling, etc) andthe symptoms of fluid retention (peripheral edema, arthralgia ormyalgia).These side effects usually appear at early stage and theincidence rate decreases over time which rarely affects dailyactivities.Long-term injection of recombinant human growth hormoneresults in antibody production in minority people, however, theaffinity of the antibody is low without exact clinical significance,The antibody may be induced if the anticipant effect of growth is notachieved, which may affect the efficacy if the affinity is over 2mg/L. CONTRAINDICATIONS Children with closure of epiphysis are forbidden.Patients with the progressive symptoms of tumor are forbidden.Critical ill patients in acute shock stage of serioussystematic infection are forbidden. STORAGE Keep at 2-8 Degrees Celsius in the refrigerator, away from light.Before reconstitution:--If refrigerated between 2-8 Degrees Celsius, it's good until expiration date.--At room temperature (under 37oC) it's good for over 30 days.After reconstitution:--Use Bacteriostatic Water to reconstitute and keep in 2-8oC, it willbe good for 20 days.--Use Sterile Water to reconstitute and keep in 2-8oC. it will be goodfor 72 hours. PACKAGE Tube-shaped antibiotics glass bottle, 10 bottles/inner box. SHELF LIFE Two years.


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